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Table 2 Baseline values for lean and non-lean NAFLD patients between genders

From: Clinical characteristics of lean and non-lean non-alcoholic fatty liver disease: a cross-sectional study

 

Female

Male

lean (n = 442)

non-lean (n = 2544)

Z/ × 2

P

lean (n = 474)

non-lean (n = 8117)

Z/ × 2

P

Age

54 (46, 60)

54 (46, 59)

0.545

0.928

50 (40, 59)

49 (40, 56)

1.52

0.02

Hb, g/L

133.5 (128, 139)

134 (128, 140)

0.958

0.318

153 (147, 159.25)

155 (149, 162)

2.095

 < 0.001

PLT, × 109/L

233 (201, 271.25)

242 (205, 281)

1.421

0.035

222.5 (189, 263)

226 (192, 262)

0.86

0.451

TP, g/L

73.7 (70.8, 76.6)

73.2 (70.4, 76)

1.04

0.23

73.35 (70.1, 76.5)

73.2 (70.4, 76.2)

0.696

0.719

ALB, g/L

46.8 (44.9, 48.6)

45.8 (44.2, 47.6)

3.097

 < 0.001

47.75 (45.98, 49.63)

47.4 (45.7, 49.2)

1.918

0.001

GLB, g/L

26.9 (24.58, 23.9)

27.3 (25, 29.6)

1.251

0.087

25.5 (23.2, 27.53)

25.8 (23.5, 28.1)

1.397

0.04

TB, μmol/L

12.6 (10.5, 15.43)

12 (9.8, 14.9)

1.875

0.002

13.55 (11, 18.1)

13.9 (11.1, 17.6)

0.848

0.468

CB, μmol/L

3.7 (2.8, 4.8)

3.6 (2.8, 4.6)

0.716

0.685

4.3 (3.2, 5.8)

4.4 (3.4, 5.7)

0.883

0.416

ALT, U/L

19 (14, 25)

21 (16, 29)

2.15

 < 0.001

25.5 (19, 35)

31 (22, 45)

3.574

 < 0.001

AST, U/L

22 (19, 27.25)

23 (19, 28)

1.081

0.193

24 (20, 29)

26 (21.5, 32)

2.729

 < 0.001

GGT, U/L

16 (13, 23)

18 (14, 27)

2.081

 < 0.001

27 (19, 41)

32 (23, 51)

3.178

 < 0.001

ALP, U/L

69 (56, 85)

70 (57.25, 86)

1.012

0.258

69.5 (59, 82.25)

69 (59, 81)

0.637

0.813

TG, mmol/L

1.26 (0.9.1.85)

1.42 (1.03, 2.04)

2.49

 < 0.001

1.49 (1.08, 2.29)

1.76 (1.24, 2.64)

2.721

 < 0.001

TC, mmol/L

5.12 (4.58, 5.87)

5.17 (4.56, 5.82)

0.638

0.81

4.96 (4.31, 5.63)

5.03 (4.43, 5.67)

1.411

0.037

HDL-C, mmol/L

1.47 (1.22, 1.71)

1.35 (1.16, 1.57)

3.203

 < 0.001

1.22 (1.04, 1.42)

1.13 (0.97, 1.3)

3.356

 < 0.001

LDL-C, mmol/L

3.04 (2.53, 3.6)

3.09 (2.58, 3.62)

0.889

0.409

2.89 (2.42, 3.51)

3.04 (2.53, 3.57)

1.924

0.001

BUN, mmol/L

4.63 (3.86, 5.52)

4.66 (3.91, 5.57)

0.499

0.965

4.87 (4.17, 5.68)

4.99 (4.27, 5.85)

1.22

0.102

Cr, μmol/L

57.2 (51.58, 62.1)

55.9 (50.7, 61.7)

1.085

0.189

75.95 (68.5, 83.73)

76.8 (69.9, 84.5)

1.086

0.189

UA, μmol/L

279.4 (244.75, 323.2)

297.25 (257.9, 345.68)

2.46

 < 0.001

383.45 (315.4, 435.45)

403.7 (351.3, 464.75)

2.718

 < 0.001

FBG, mmol/L

4.96 (4.66, 5.31)

5.1 (4.72, 5.54)

2.005

0.001

4.97 (4.6, 5.36)

5.08 (4.7, 5.6)

2.084

 < 0.001

BMI, kg/m2

22.2 (21.5, 22.6)

25.8 (24.4, 27.5)

19.405

 < 0.001

22.2 (21.7, 22.6)

26.6 (25.1, 28.4)

21.162

 < 0.001

HbA1c, %

5.5 (5.2, 5.7)

5.6 (5.3, 5.9)

2.66

 < 0.001

5.4 (5.2, 5.7)

5.5 (5.3, 5.8)

1.815

0.003

CAP, db/m

253 (246, 260.25)

264 (251, 282)

6.468

 < 0.001

256 (248, 262)

274 (255, 290)

8.93

 < 0.001

LSM, kPa

5.5 (4.8, 6.3)

5.6 (4.8, 6.5)

1.52

0.02

5.6 (4.7, 6.4)

5.7 (4.9, 6.6)

1.251

0.087

TyG

8.53 (8.16, 9.96)

8.67 (8.34, 9.09)

2.66

 < 0.001

8.68 (8.33, 9.14)

8.89 (8.51, 9.34)

3.219

 < 0.001

TyG-BMI

187.74 (178.4, 197.79)

225.05 (210.12, 244.61)

13.814

 < 0.001

191.86 (183.19, 202.35)

236.9 (219.36, 259.32)

15.473

 < 0.001

TG/HDL-C

0.83 (0.55, 1.43)

1.06 (0.69, 1.67)

3.007

 < 0.001

1.26 (0.81, 2.06)

1.56 (1, 2.57)

3.057

 < 0.001

FIB-4

1.12 (0.84, 1.55)

1.11 (0.8, 1.48)

1.142

0.147

1 (0.75, 1.46)

1 (0.73, 1.35)

1.313

0.064

APRI

0.23 (0.18, 0.32)

0.24 (0.19, 0.32)

0.63

0.822

0.27 (0.2, 0.35)

0.29 (0.23, 0.38)

2.386

 < 0.001

AST/ALT

1.18 (0.95, 1.45)

1.07 (0.86, 1.33)

2.931

 < 0.001

0.93 (0.71, 1.16)

0.81 (0.65, 1.04)

3.229

 < 0.001

Hypertension, n (%)

77 (17.46%)

717 (28.18%)

22.348

 < 0.001

91 (19.2%)

2272 (28%)

17.363

 < 0.001

Diabetes, n (%)

15 (3.4%)

222 (8.73%)

14.656

 < 0.001

41 (8.65%)

856 (10.55%)

1.722

0.216

  1. Continuous variables were shown as mean ± SD or median (interquartile range), and categorical variables were expressed as counts (percentage)
  2. Hb hemoglobin, PLT platelet, TP total protein, ALB albumin, GLB globulin, ALT alanine aminotransferase, AST aspartate aminotransferase, TB total bilirubin, DB direct bilirubin, GGT gamma-glutamyl transpeptidase, ALP alkaline phosphatase, Cr creatinine, BUN blood urea nitrogen, UA Uric Acid, FBG fasting blood glucose, TG triglyceride, CHOL cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, HbA1c glycosylated hemoglobin, TyG triglyceride and glucose index, TyG-BMI triglyceride glucose-body mass index, FIB-4 fibrosis-4 score, APRI aspartate aminotransferase to platelet ratio index, CAP controlled attenuation parameter, LSM liver stiffness measurement
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Nutrition & Metabolism

ISSN: 1743-7075

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