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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: Metabolic profiles and prediction of failure to thrive of citrin deficiency with normal liver function based on metabolomics and machine learning

Fig. 1

Serum metabolomic signature in NICCD. (A) OPLS-DA score plots showing clustering and dispersion between NICCD vs. controls (B) Volcano plot of DEMs with upregulated (red), downregulated (blue), and non-significant metabolites (gray). (C) Hierarchical cluster analysis heatmaps of DEMs. (D) Enrichment analysis. 2-HG, 2-Hydroxyglutarate; KIV, Ketoisovaleric acid; 2-MCA, 2-Methylcitric acid; KMVA, 2-Keto-3-methylvaleric acid; HIVA, 2-Hydroxyisovaleric acid; 4-HPLA, 4-Hydroxyphenyllactic acid; GAA, Guanidineacetic acid

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Nutrition & Metabolism

ISSN: 1743-7075

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